Global Stochastic Optical Reconstruction Microscopy Market Research Reports, Size, Share and trends up to 2021
The global Stochastic Optical
Reconstruction Microscopy (STORM) market is classified on the basis of product
type, application and geography.
Super-resolution microscopy is a form of light microscopy.
Super-resolution techniques allow images to be taken with a higher resolution
than the diffraction limit. There are different types of super-resolution
microscopy such as stochastic optical reconstruction microscopy (STORM),
structured illumination microscopy (SIM), stimulated emission depletion
microscopy (STED), coherent anti-strokes Raman scattering microscopy (CARS),
photo-activated localization microscopy (PALM), and reversible storable optical
fluorescence transitions (RESOLFT).
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In conventional fluorescence
microscopy where all fluorophores in the sample are fluorescent, their
diffraction limited images overlap, creating a smooth but blurred picture.
STORM is based on stochastic switching of single-molecule fluorescence signal.
STORM utilizes fluorescent probes that can switch between fluorescent and dark
states so that in every snapshot, only a small, optically resolvable fraction
of the fluorophores is detected. This assists determining their positions with
high accuracy from the center positions of the fluorescent spots. With multiple
snapshots of the sample, each capturing a random subset of the fluorophores, a
final super-resolution image can be reconstructed from the gathered
position.
Some of the applications of STORM
include imaging cell surface or distinct features particularly useful for
membranes, receptors, adhesion complexes, protein clustering, and so on.
Getting quantitative/statistical information regarding protein distributions in
sub-diffraction-limit structures that are difficult to get to with other
techniques. Effective imaging depends on the reconstruction algorithm and
necessitates the precise selection of dyes, embedding condition and high
labelling density.
The factors that propel the market
growth include increasing research and development activities. In addition,
high-tech innovations such as super resolution microscopy, high-throughput
techniques, and digitization of microscopes are also fueling the growth of the
market. Moreover, government funding also plays a significant role to uplift
the market growth. On the other hand, there are also factors that hamper the
growth of the market such as high price of advanced microscopes and lack of
technical expertise.
On the basis of product type, the
market research report is classified as dSTORM – Alexa Fluor 488-568, dSTORM – Alexa
Fluor 597-750 and nSTORM. On the basis
of application, the Stochastic Optical Reconstruction Microscopy market is
classified as academic institutes, chemical industry, semiconductor and medical
care. On the basis of geography, the Stochastic Optical Reconstruction
Microscopy market Read More...
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